Pilot & production-scale glass reactors - chemReactor BR/GR

Glass reactor systems for API synthesis, small-scale production and pilot plant applications
Volume: 15 / 30 / 60 liter
Pressure: -1.0 (FV) to +0.5 bar
Temperature: -60°C (-90°C) to +200°C
Material: Borosilicate glass 3.3 / glass lined steel / PTFE / PFA / Tantalum
Customized setups are available.

The BR/GR type chemReactor is a basic pilot reactor system for chemical process development, scale-up, process simulation and kilo-scale cGMP production in batch and semi-batch operation.

Performance and reliability are key elements in the explosion proof design of Buchi glass reaction systems. The inert materials allow safe processing in an inert atmosphere of a wide range of solvents and acids in a completely sealed glass reaction system under full vacuum. Multiple chemical reaction steps are performed safely in the same setup.

The chemReactor BR/GR system consists of:

• Reactor: solid jacketed full view glass reactor to easily control and improve chemical reactions by visual observation.
• Distillation glass overhead: built with buchiflex components (unique flexible ball - socket joints) for multiple, reliable processes under full vacuum.

Typical applications:

• Chemical synthesis
• Extraction / evaporation
• Purification / crystallization
• Separation
• API manufacturing
• Peptide production
• Process development
• Scale-up
• Cryogenic reactions
• Small scale production
• Pilot plant / kilo lab