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Tangential flow filtration system - Tytan

Solaris Biotech Solutions

A completely customizable pilot and industrial system – the Tangential Flow Filtration (TFF) TYTAN. The tangential flow filtration or cross flow filtration TYTAN develops a process in which unfiltered product (retentate) flows tangentially across a membrane surface. Any dissolved or undissolved permeate component smaller than the membrane passes through it, while larger suspended particulates remain in the retentate flow. 

Features: 

  • Ceramic and polymeric membranes are available in pore sizes from 0.04µm to 1.2µm   
  • Up to 12 modules are available 
  • Stainless steel (AISI 316 and AISI 304) manufacturing 
  • 21,5” HMI touch panel 
  • Pre-filter (strainer)   
  • Dry running protection over- and under-pressure protection 
  • Automatic backwash 

Additional Features: 

  • Turnkey: starting from the clients’ URS, Solaris manufactures tailored TFF solutions, to be applied to the recovery and separation of biotechnological products in downstream operations. 
  • Reliability: with TYTAN, customers benefit from custom-designed vessels with smart sensor technology integrated for optimal process workflow. 
  • Filtration Membranes: our filtration specialists are always ready to suggest the best membrane in terms of materials, geometrical configuration and operative parameters to: concentrate on the best efficiency, avoid gel layer problem, optimize the cost/profit ratio, minimize scale up cost. 
  • The Systems: the systems are fully suitable for inline CIP and compliant to the most current GMP regulations and PED standards. The measurement and control system is based on a SCADA supervisory Lab View, SFC-10, connected to a PLC.  

Software: 

  • Innovative SCADA software LEONARDO 3.0: a smart and user-friendly controller designed to provide a high level of automated management of the fermentation/cultivation processes. 
  • Data extraction in .csv format 
  • Remote access via PC, tablet or smartphone, with QR code scanning or dedicated portal 
  • Remote control for after sale assistance 
  • Synoptic page with manual operation and active monitoring of relevant process parameters  
  • Save, load or delete recipes 
  • Continuous trend graphs representation to track, print and export data on up to 6 processes and set point variables 
  • Attribution to the variables of maximum and minimum values to act as alarm thresholds 

TFF Configuration Options: 

Based on specific process / product needs, TFF configuration can integrate several different membrane types including: 

  • Spiral wound 
  • Hollow fiber (polymeric) 
  • Cassettes (polymeric) 
  • Tubular (ceramic) 

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