Quantitative determination of carbamazepine and two of its metabolites in serum.
Carbamazepine (5H-dibenzepine-5-carboxamide) is used as an analgesic and anticonvulsant. The analysis of carbamazepine and its metabolites is required in various fields such as biochemistry, clinical, bio-equivalence and bio-availability.
Quantitative determination of carbamazepine and of its metabolites is also needed for therapeutic drug monitoring in human medicine.