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Glass process equipment

Glass-lined steel reactor: 250 to 10'000 liter
Pressure: -1.0 (FV) to +0.5 bar
Temperature: -60°C (-90°C) to +200°C
Material: Borosilicate glass 3.3 / glass-lined steel / PTFE / PFA / Tantalum

Production-scale reactor systems are mainly used as process equipment for pharmaceutical and chemical manufacturing. These systems consist of glass-lined reactors and distillation overheads made of borosilicate glass and are always specifically engineered according to customers’ specifications.

The distillation overhead is typically composed of a vapor duct, heat exchangers, feeders and receivers as well as connecting piping.

Feeders and receivers are made of glass for smaller volumes and of glass-lined steel for larger setups. Two different types of heat exchangers are typically used: spiral condenser (glass) and shell and tube heat exchangers. Shell and tube type heat exchangers are built with inner tubes made of borosilicate glass, glass-lined steel, silicon carbide (SiC), tantalum or other metals, depending on process parameters and other requirements.

The design varies between multi-purpose product / process specific setups. These apparatus can be operated at full vacuum and low pressure. A broad range of chemical reactions can be performed and a large variety of chemicals can be processed, thanks to the highly corrosion resistant materials in contact with the process media.

Typical applications:

  • Chemical synthesis
  • Extraction / evaporation
  • Crystallization
  • Separation
  • Vacuum distillation / reflux distillation
  • Rectification
  • API manufacturing
  • Peptide synthesis
  • Fine chemical production
  • Solvent recovery

Büchi’s 3-D engineering capabilities enable the integration / combination of glass-lined reactors of different suppliers with Büchi’s distillation glass overheads into a complete reaction system.

Benefit from Büchi’s long-term experience in the design, engineering and manufacturing of safe and reliable high-performance glass process equipment.

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